G-CSF Administration after the Intraosseous Infusion of Hypertonic Hydroxyethyl Starches Accelerating Wound Healing Combined with Hemorrhagic Shock
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منابع مشابه
G-CSF Administration after the Intraosseous Infusion of Hypertonic Hydroxyethyl Starches Accelerating Wound Healing Combined with Hemorrhagic Shock
OBJECTIVE To evaluate the therapeutic effects of G-CSF administration after intraosseous (IO) resuscitation in hemorrhagic shock (HS) combined with cutaneous injury rats. METHODS The rats were randomly divided into four groups: (1) HS with resuscitation (blank), (2) HS with resuscitation + G-CSF (G-CSF, 200 μg/kg body weight, subcutaneous injection), (3) HS with resuscitation + normal saline ...
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Introduction: In the recent years, effect of hypertonic solution in resuscitation of shock has been shown by clinical and laboratory studies. On the other hand ATP-MgCl2 is used for better tissue perfusion and cardiac output in shock. The aim of this study is evaluation of ATP-MgCl2 with hypertonic solution in resuscitation of hemorrhagic shock. Materials and Methods: In this experimental stud...
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An animal model was designed to study the effect of large volume Hypertonic Solutions (HTS) for resuscitation following a hypovolemic shock. Resuscitation in hypovolemic animals was performed by infusion of 15 ml/kg of normal saline (group I), 5% sodium bicarbonate (NaHCO3) (group II), 5% sodium chloride (NaCI) and 7.5 % NaHCO3 1:1 VN (group III), 5% NaC1 (group IV), and 5% NaCl and 5% serum a...
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BACKGROUND Following severe trauma, treatment of cutaneous injuries is often delayed by inadequate blood supply. The aim of the present study was to determine whether granulocyte-colony stimulating factor (G-CSF) protects endothelial cells (ECs) and enhances angiogenesis in a rat model of hemorrhagic shock (HS) combined with cutaneous injury after resuscitation. MATERIAL AND METHODS The HS rats...
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ژورنال
عنوان ژورنال: BioMed Research International
سال: 2016
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2016/5317630